What is Entamizole Syrup?
Entamizole syrup is a prescription anti-infective medicine that doctors commonly use to treat intestinal infections, especially those caused by amoeba and mixed gut infections. Doctors often recommend the syrup form for children, elderly patients, or adults who find tablets difficult to swallow.
Use it only when a healthcare professional suspects or confirms an infection.
How Entamizole Syrup Works
Entamizole syrup contains two active medicines that work together:
- One component clears amoeba present inside the intestine.
- The other treats infections that have spread to the intestinal tissues and also acts against certain bacteria.
Because intestinal infections can involve organisms in different locations, this combination helps achieve better symptom control and lower relapse risk.
Composition of Entamizole Syrup
Active ingredients include:
- Diloxanide furoate: targets amoeba inside the gut
- Metronidazole: treats tissue infection and certain bacteria
This combination is widely used in amoebiasis and infectious dysentery.
Why Doctors Prefer Syrup Form
- Easier administration in children
- Accurate dose adjustment based on age and weight
- Better option for patients with swallowing difficulties
Uses of Entamizole Syrup
Doctors may prescribe Entamizole syrup for:
- Amoebic diarrhea
- Dysentery (blood or mucus in stool)
- Infection-related loose motion
- Stomach cramps linked with gut infection
- Mixed gastrointestinal infections
This medicine does not treat routine diarrhea caused by viruses or food intolerance.
When Entamizole Syrup is Prescribed
A doctor may consider Entamizole syrup if a patient has:
- Persistent diarrhea
- Blood or mucus in stool
- Abdominal cramps with infection signs
- Symptoms not improving with fluids alone
Avoid Entamizole Syrup in the following situations.
- Viral gastroenteritis without infection
- Known allergy to ingredients
- Severe liver disease (unless advised)
- Early pregnancy without medical consultation
How to Take Entamizole Syrup
- Shake the bottle well before each dose
- Measure carefully using a proper measuring spoon or syringe
- Taking it after food may help reduce nausea
Dosage Information
- Children: Dose depends on age and body weight, and must be prescribed
- Adults: Liquid dosing is used when tablets are unsuitable
Parents should never guess or self-adjust the dose.
Possible Side Effects
Common side effects include
- Mild nausea
- Metallic taste
- Temporary stomach discomfort
Seek medical help immediately if there is
- Severe rash or swelling
- Persistent vomiting
- Confusion or extreme weakness
- Yellowing of eyes or skin
Important Safety Warnings
- Avoid alcohol completely during treatment
- Use cautiously in liver disease
- Maintain good hydration, especially in children
Drug Interactions
- Alcohol (can cause a severe reaction)
- Blood thinners (may increase bleeding risk)
- Some seizure medications
Drug Interaction of Ciprofloxacin (Novidate) with Entamizole Syrup
When Ciprofloxacin (Novidat) is used along with Entamizole syrup, the combination should be guided by a healthcare professional. Taking both medicines together may increase digestive side effects such as nausea or abdominal discomfort, so maintaining good fluid intake is important. Always inform your doctor about all medicines being used.
Use in Special Populations
- Children: Use only under medical supervision
- Pregnancy: The doctor must assess the benefit vs risk
- Breastfeeding: Professional advice required
- Elderly: Higher sensitivity to side effects
Storage Instructions
- Store in a cool, dry place
- Keep the bottle tightly closed
- Do not use after the expiry date
Frequently Asked Questions
Entamizole syrup is used to treat intestinal infections, especially those caused by amoeba and mixed gut infections.
Yes, Entamizole syrup can be used in children, but only when prescribed by a doctor.
Entamizole syrup treats the cause of infection, not the immediate symptoms. Improvement usually starts within 1–3 days, but hydration with ORS is equally important.
Entamizole syrup is usually better tolerated after food, as this helps reduce nausea and stomach discomfort. Always follow your doctor’s specific instructions.
Common side effects include mild nausea, metallic taste, and temporary stomach upset. Serious reactions are rare but require urgent medical attention if symptoms like severe rash, confusion, or yellowing of the eyes appear.

